Tehran University of Medical Sciences Journal of Arthropod-Borne Diseases 2322-1984 12 4 2018 10 12 378 386 Aytekin Cikman Department of Medical Microbiology, Erzincan University School of Medicine, Erzincan, Turkey Merve Aydin Department of Medical Microbiology, Erzincan University School of Medicine, Erzincan, Turkey AND Department of Medical Microbiology, KTO Karatay University School of Medicine, Konya, Turkey Baris Gulhan Department of Medical Microbiology, Erzincan University School of Medicine, Erzincan, Turkey Faruk Karakecili Department of Infectious Diseases, Erzincan University School of Medicine, Erzincan, Turkey Levent Demirtas Department of Internal Medicine, Erzincan University School of Medicine, Erzincan, Turkey Ozan Arif Kesik Department of Geography, Faculty of Arts and Sciences, Erzincan University, Erzincan, Turkey 2018 12 12 Background: We aimed to determine the geographical features and seroprevalence of Borrelia burgdorferi in Erzincan, Turkey, which has a high tick population due to its geographical position and climatic conditions. Methods: From January to December 2014, 368 people living in Erzincan, northeastern Turkey were enrolled. B. burgdorferi IgG antibodies were investigated in the collected serum samples using the ELISA method in 2015. Positive and borderline results were confirmed using the Western Blot (WB) method.  Results: Borrelia burgdorferi IgG positivity was found to be 4.1% by ELISA and 2.17% by WB. Of the seropositive people according to WB, 25% resided in areas within 2000m of rivers, 50% in areas with a slope of 0–5°, and 62.5% in areas with an altitude of lower than 1500 meters. Conclusion: The seroprevalence of Lyme borreliosis was high in Erzincan, particularly among people engaged in animal husbandry in rural areas. In addition, the seroprevalence of Borrelia varied according to geographical features, increasing in areas with a lower slope and altitude. https://jad.tums.ac.ir/index.php/jad/article/view/1027 https://jad.tums.ac.ir/index.php/jad/article/download/1027/425