Tehran University of Medical Sciences Journal of Arthropod-Borne Diseases 2322-1984 13 2 2018 10 12 214 223 Samin Madreseh-Ghahfarokhi Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Amir Dehghani-Samani Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran AND Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran Yaser Pirali Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran Azam Dehghani-Samani Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran 2019 06 23 Background: Rhipicephalus bursa is a hard tick with importance in transmission of tick-borne diseases and zoono­sis. Natural products are excellent alternative to pesticides. In this study for the first time, lethal and repellent activity of Zingiber officinalis and Eucalyptus globulus against Rh. bursa were studied. Methods: In July till September of 2017, essential oils were extracted in Shahrekord University, Iran from fresh plant materials and engorged mature ticks were collected from infested sheep herd located in Saman, Iran. Ticks were challenged by different concentrations of essential oils including 300, 500 and 800µl/ml and 1 (pure) singly and/or in combination. Percentages of killed and repellent ticks as efficacy of acaricidal and repellent activity of es­sential oils against Rh. bursa were calculated and analyzed statistically. Results: Efficacy of eucalyptus essential oils was more in whole concentrations and its highest performance was observed in concentration 1 (pure). Efficacies of ginger and combined essential oils were different for each concen­tration but their highest efficacies were observed in concentration 1 (pure), too. Conclusion: This study showed considerable values of acaricidal and repellent activity against Rh. bursa for both essential oils singly and in combination, so they can be considered as potent lethal/repellent agents for control of ticks, but more studies need for this purpose, study on lethal/repellent activity of these essential oils and/or other plants against other important arthropods can be considered as subjects for next experiments. https://jad.tums.ac.ir/index.php/jad/article/view/1143 https://jad.tums.ac.ir/index.php/jad/article/download/1143/458