Tehran University of Medical Sciences Journal of Arthropod-Borne Diseases 2322-1984 15 4 2022 09 04 349 357 Amrollah Azarm Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad Nasrabadi Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Fatemeh Shahidi Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Awat Dehghan Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Fateme Nikpoor Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Alireza Zahraie-Ramazani Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Seyede Maryam Molaeezadeh Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Faramarz Bozorgomid Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ghazal Tashakori Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Hassan Vatandoost Department of Environmental Chemical Pollutants and Pesticides, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran 2022 09 04 2022 09 04 Background: Culex pipiens complex is considered as a vector of some important diseases suchas West Nile fever, equine encephalitis, Rift valley fever, St. Louis encephalitis, Elephanthiasis and avian malaria in the world. The main measure for vector control is using insecticides. High use of insecticides caused resistance in the populations. The aim of this study was to review the status of insecticide resistance in the vector. Methods: Insecticide resistance in this species was found by the available papers and map of the data for carbamates, organochlorine, organophosphates, pyrethroids, microbial and insect growth regulator insecticides were done. An intensive search of scientific literature was done in “PubMed”, “Web of Knowledge”, “Scopus”, “Google Scholar”, “SID”, and related resources. Results: Results showed that a wide variety of resistance to different insecticides in the country. Due to importance of this species in transmission of diseases. Discussion: resistance management strategies should be further considered to prevent from in secticide resistance and replacement of novel approach for vector control. https://jad.tums.ac.ir/index.php/jad/article/view/1577 https://jad.tums.ac.ir/index.php/jad/article/download/1577/578