Tehran University of Medical Sciences Journal of Arthropod-Borne Diseases 2322-1984 18 1 2024 04 27 1649 1649 Shahla Afrasiabian Zoonoses Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Saber Esmaeili Department of Epidemiology and Biostatics, Research Centre for Emerging and Reemerging Infectious Dis¬eases, Pasteur Institute of Iran, Tehran, Iran, National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, KabudarAhang, Hamadan, Iran Katayon Hajibagheri Department of Infectious Diseases, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran Nooshin Hadizadeh Department of Cardiovascular Medicine, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran Gohar Lotfi Department of Infectious Diseases, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran Arshad Veysi Zoonoses Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran 2023 05 23 2024 03 13 Background: Q fever is a contagious zoonotic disease which is caused by a gram-negative and an intracellular cocco­bacillus known as Coxiella burnetii that ticks play role in its transmission. Endocarditis is the most common conse­quence of chronic Q fever. Methods: Here we report a case of endocarditis caused by Q fever. The patient is a 67-year-old, and she had coronary artery bypass graft (CABG) and aortic valve replacement surgery. Results: The result of echocardiography showed a suspicious mass (Vegetation) on the implanted valve. Based on la­boratory and clinical assessments, endocarditis caused by C. burnetii was the final diagnosis. Conclusion: Q fever is a tick-transmitted pathogen that has been known as an important cause of culture-negative en­docarditis in Iran, and more attention needed to be paid to this disease in Iran by the healthcare system and physicians. https://jad.tums.ac.ir/index.php/jad/article/view/1649 https://jad.tums.ac.ir/index.php/jad/article/download/1649/646