Tehran University of Medical Sciences Journal of Arthropod-Borne Diseases 2322-1984 19 2 2025 11 19 157 164 Tooran Nayeri Infectious and Tropical Diseases Research Center, Dezful University of Medical Sciences, Dezful, Iran Kiana Yahyaei Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran Nasim Khajavian Department of Epidemiology and Biostatistics, Social Determinants of Health Research Center, School of Health, Gonabad University of Medical Sciences, Gonabad, Iran Mohamad Hasan Minooeianhaghighi Department of Medical Microbiology, Faculty of Medicine, Infectious Diseases Research Center, Gona¬bad University of Medical Science, Gonabad, Iran Hamideh Mohammadzadeh Department of Dermatology, Gonabad University of Medical Sciences, Gonabad, Iran Hossein Pazoki Department of Medical Microbiology, Faculty of Medicine, Infectious Diseases Research Center, Gona¬bad University of Medical Science, Gonabad, Iran 2025 04 18 2025 11 16 Background: Scabies, caused by Sarcoptes scabiei, is common in Iran; however, epidemiological data from Gonabad City are scarce. Therefore, this study was conducted to determine the prevalence of scabies in patients referred to the derma­tology clinic of Allameh Bohlool Gonabadi Hospital in Gonabad City and to investigate its associated risk factors. Methods: A cross-sectional analysis was conducted in 2024 on 734 patients presenting with pruritic eruptions and itchy rashes. The diagnosis of scabies was confirmed in 98 patients by identifying S. scabiei mites, eggs, or fecal pellets through light microscopic examination of skin scrapings. Data from these confirmed cases were analyzed using SPSS v.25 to describe their characteristics. Results: Among the 734 patients screened, 98 were confirmed to have scabies (13.4%). Analysis of these 98 cases re­vealed that the majority were female (64.3%, 63/98). The highest frequency of cases was observed in individuals aged 16 years and younger. Assessment of clinical presentation revealed that 55.1% (54/98) of cases presented with moderate lesions. A high proportion of cases were also among women, people with low levels of education and unemployed people. Conclusion: This study identified a total of 98 scabies cases among 734 patients screened in Gonabad City. The infestation was significantly associated with being female, having a lower level of education, and unemployment. These findings highlight a distinct epidemiological pattern of scabies in this underserved region and underscore the need for targeted community screening and health education, particularly among the affected demographic groups. Further analytical studies are needed to confirm true risk factors at the population level. https://jad.tums.ac.ir/index.php/jad/article/view/1842 https://jad.tums.ac.ir/index.php/jad/article/download/1842/697