A Review on Scorpionism in Iran

  • Rouhullah Dehghani Social Determinants Research Center of Health and Engineering Department of Environmental Health, Medical Science University of Kashan, Kashan, Iran
  • Esmail Charkhloo Department of Environment Health Engineering, Faculty of Health, Jiroft University of Medical Sciences, Jiroft, Iran
  • Nedasadat Seyyedi-Bidgoli Social Determinants Research Center of Health and Engineering Department of Environmental Health, Medical Science University of Kashan, Kashan, Iran
  • Elahe Chimehi Social Determinants Research Center of Health and Engineering Department of Environmental Health, Medical Science University of Kashan, Kashan, Iran
  • Maedeh Ghavami-Ghameshlo Social Determinants Research Center of Health and Engineering Department of Environmental Health, Medical Science University of Kashan, Kashan, Iran
Keywords: Province, Sting agent, Scorpion, Iran


Background: Scorpions are one of the most important venomous animals in Iran. Their sting has more prevalence in the south and southwest areas. The aim of this study was to introduce their sting agent species in the country. Methods: Data were extracted by a mini review on scorpion stinging articles in Iran until early 2018 and then the sting agent species in each area were studied. Geographical and provincial distribution of each species also was provided. Results:  Twelve scorpion species are causative agents of sting. According to their deadly rate and clinical symptoms, some of them are considered the most dangerous venomous animals in Iran. Some death cases have been reported be­cause of the sting of 3 species of Hemiscorpius lepturus, H. acanthocercus and Androctonus crassicauda. Remaining species have not deadly sting but because of their frequency, they encounter the individuals and cause the stinging. Conclusion: The highest number of sting agents is in Khuzestan, however Gilan and Mazandaran have the lowest fre­quency. Because of the high prevalence of sting agent species in that province, the necessity of providing control and prevention programs is very important.


1. Chippaux JP, Goyffon M (2008) Epidemi-ology of scorpionism: a global apprais-al. Acta Trop. 107(2): 71–79.
2. Motevalli Haghi F, Dehghani R (2017) A Review of Scorpions Reported in Iran. J Mazandaran Univ Med Sci. 27(151): 213–226.
3. Dehghani R, Hoseindoost G, Seyyedi Bidgoli N, Zamani M, Ghadami F (2017) Study of Pests of Residential Complex and Stu-dent Dormitories of Kashan University of Medical Sciences. J Ent Res. 41(3): 311–316.
4. Ahmadimarzale M, Sabuhi H, Sabahi Bidgoli\ M, Dehghani R, Hoseindoost G, Mesgari L (2017) Study of Scorpion Species Abun-dance in cities Aran and Bidgol and Kashan, Isfahan, Iran. J Ent Res. 41(3): 337–342.
5. Dehghani R, Kamiabi F, Mohammadzadeh N (2017) Burrowing Habits of two Ar-thropods; Odenthobutus doriae and Hemilepistus shirazi in desert soils of Isfahan, Iran, J Ent Res. 41(2): 113–118.
6. Dehghani R, Kamiabi F (2017) Frequency of Odonthubutus doriae Thorell 1876 nests in desert soils, Esfahan, Iran. J Ent Res. 41(1): 13–18.
7. Yousef-Mogaddam M, Dehghani R, Enayati AA, Fazeli-Dinan M, Vazirianzadeh B, Yazdani-Cherati J, Motevalli Haghi F (2017) Scorpion Fauna (Arachnida: Scor-piones) in Darmian County, Iran (2015–2016). J Mazandaran Univ Med Sci. 26 (144): 108–118 (Persian)
8. Dehghani R, Fathi B (2012) Scorpion sting in Iran: A review. Toxicon. 60(5): 919–933.
9. Dehghani R, Kassiri H (2017) Geographical Distribution of Scorpion Odontobuthus doriae in Esfahan Province, Central Iran. J Arthropod Borne Dis. 11(3): 433–440.
10. Nejati J, Mozafari E, Saghafipour A, Kiyani M (2014) Scorpion fauna and epidemio-logical aspects of scorpionism in south-eastern Iran. Asian Pac J Trop Biomed. 4(Suppl 1): S217–S221.
11. Nejati J, Saghafipour A, Mozaffari E, Key-hani A, Jesri N (2017) Scorpions and scor-pionism in Iran’s central desert. Acta Trop. 166: 293–298.
12. Yousef-Mogaddam M, Dehghani R, Enayati AA, Fazeli-Dinan M, Motevalli Haghi F (2016) Epidemiology of Scorpionism in Darmian, Iran, 2015. J Mazandaran Univ Med Sci. 26(141): 131–136. (Persian)
13. Dehghani R, Arani MG (2015) Scorpion sting prevention and treatment in ancient Iran. J Tradit Complement Med. 5(2): 75–80.
14. Nazari M, Hajizadeh MA (2016) Faunistic
Study on Scorpions and the Epidemiology of Scorpionism in Bam, Southeast of Iran. Glob J Health Sci. 9(2): 177–182.
15. Dehghani R, Valizade R, Mahmoodi S (2016) A review of the scorpion predators and the introduction of Scarites subterraneus, as a new predatory of them in Iran. J Ent Res. 40(3): 291–296.
16. Dehghani R, Khamehchian T, Miranzadeh MB (2007) Surveying on the Biologic be-haviors of Hemiscorpius lepturus (Peters, 1861) scorpion in laboratory (Khuzestan, Iran) (Scorpions: Hemiscorpiidae). Pak J Biol Sci. 10(18): 3097–3102.
17. Dehghani R (2017) Solpugidophobia in Iran: Real or Illusion. J Biol Today's World. 6(3): 46–48.
18. Dehghani R, Djadid ND, Shahbazzadeh D, Bigdelli S (2009) Introducing Compsobu-thus matthiesseni (Birula, 1905) scorpion as one of the major stinging scorpions in Khuzestan, Iran. Toxicon. 54(3): 272–275.
19. Dehghani R, Sharif A, Madani M, Kashani HH, Sharif MR (2016) Factors Influenc-ing Animal Bites in Iran: A Descriptive Study. Osong Public Health Res Perspect. 7(4): 273–277.
20. Dehghani R, Dadpour B, Keyler D, Pan-jehshahi M, Jazayeri M, Mehrpour O, Tamijani AH (2016) A survey on Non-Venomous Snakes in Kashan (Central Iran). J Biol Today's World. 5(4): 65–75.
21. Dehghani R, Mehrpour O, Shahi MP, Jaza-yeri M, Karrari P, Keyler D, Zamani N (2014) Epidemiology of venomous and semi-venomous snakebites (Ophidia: Vi-peridae, Colubridae) in the Kashan City of the Isfahan Province in Central Iran. J Res Med Sci. 19(1): 33–40.
22. Dehghani R, Fathi B, Shahi MP, Jazayeri M (2014) Ten years of snakebites in Iran. Toxicon. 90: 291–298.
23. Dehghani R, Sharif A, Assadi MA, Haddad-Kashani H, Sharif MR (2016) Fungal flora in the mouth of venomous and non-ven-omous snakes. Comp Clin Pathol. 25:1207–1211.
24. Jalali A, Rahim F (2014) Epidemiological review of scorpion envenomation in Iran. Iran J Pharm Res. 13(3): 743–756.
25. Shahi M, Mousavi SH, Navidpour SH, Raf-inejad J (2015) A Review Study on Dis-tribution and Medical Importance of Hemiscorpius Peters, 1861 in Iran. J Ma-zandaran Univ Med Sci. 24(120): 107–124 (Persian).
26. Dehghani R, Rafinejad J, Fathi B, Panjeh-Shahi M, Jazayeri M, Hashemi A (2017) A Retrospective Study on Scropionism in Iran (2002–2011). J Arthropod Borne Dis. 11(2): 184–193.
27. Dehghani R, Vazirianzadeh B, Rahimi Nasra-badi M, Moravej SA (2010) Study of scor-pionism in Kashan in central of Iran. Pak J Med Sci. 26(10): 955–958.
28. Shahbazzadeh D, Amirkhani A, Djadid ND, Bigdeli S, Akbari A, Ahari H, Amini H, Dehghani R (2009) Epidemiological and clinical survey of scorpionism in Khuzestan Province, Iran (2003). Toxi-con. 53(4): 454–459.
29. Sanaei-Zadeh H, Marashi SM, Dehghani R (2017) Epidemiological and clinical characteristics of scorpionism in Shiraz (2012–2016), development of a clinical severity grading for Iranian scorpion en-venomation. Med J Islam Repub Iran. 31: 27: 1-9.
30. Nazari M, Najafi A (2016) An Epidemio-logical Study on Scorpion Envenomation in Kazerun, Iran, 2009–2014. J Mazanda-ran Univ Med Sci. 26(140): 206–211 (Persian)
31. Mirshamsi O, Sari AR, Hosseinie S (2011) History of study and checklist of the scor-pion fauna (Arachnida: Scorpiones) of Iran. Progress in Biological Sciences. 1(2): 16–28.
32. Dehghani R, Saberi HR, Sabahi Bidgoli M, Charkhloo E, Chimehi E, Mohammadza-deh N (2018) Survey of museum beetle (Dermestes sp.) damage to the scorpion collection in the Health Faculty of Kashan University of Medical Sciences. J Ent Res. 42(2): 295–300.
33. Vatanpour H, Ahmadi F, Mirakabadi AZ, Jalali A (2012) Two Biological Active Fractions Isolated from Buthotus schach (BS) Scorpion Venom Examined on Stri-ated Muscle Preparation, In-vitro. Iran J Pharma Res. 11(3): 905–911.
34. Dehghani R, Moabed S, Kamyabi F, Hagh-doost A, Mashayekhi M, Soltani H (2008) Scorpions fauna of Kerman Province-Iran. Journal of Kerman University of Medical Sciences. 15(2): 172–181.
35. Zare-Mirakabadi A (2013) Hemiscorpius lepturus envenomation: manifestations and management with specific antivenom. Arch Razi Inst. 68(2): 91–99.
36. Radmanesh M (1990) Clinical study of Hemiscorpion lepturus in Iran. Am J Trop Med Hyg. 93(5): 327–332.
37. Moosavy SH, Shahi M, Rafinejad J, Zare S, Madani A, Navidpour S (2016) Epi-demiological aspect of scorpion sting in Bandar Abbas, Iran, during 2009–2011. Electron Physician. 8(4): 2286–2290.
38. Pipelzadeh MH, Jalali A, Taraz M, Pour-abbas R, Zaremirakabadi A (2007) An epidemiological and a clinical study on scorpionism by the Iranian scorpion Hemiscorpius lepturus. Toxicon. 50(7): 984–992.
39. Radmanesh M (1998) Cutaneous mani-festations of the Hemiscorpius lepturus sting: a clinical study. Int J Dermatolo-gy. 37: 500–507.
40. Malhotra KK, Chadha JS, Mirdehghan M, Tandon D (1978) Acute renal failure fal-lowing scorpion sting. Am J Trop Med Hyg. 27(3): 623–626.
41. Mostafazadeh B, Gorbani A, Mogaddaspour M, Khoddami Vishteh HR (2017) The effect of plasmapheresis on treating dis-seminated intravascular coagulation (DIC) caused by a Hemiscorpius lepturus (Gadim) sting. Clin Toxicol. 11: 1–6.
42. Dehghani R, Khamechian T, Vazirianza-deh B, Moravvej S (2012) Toxic effects of scorpion, Hemiscorpius lepturus (Hemiscorpiidae) venom on mice. J Anim Plant Sci. 22(3): 593–596.
43. Ghafourian M, Ganjalikhanhakemi N, Hem-mati AA, Dehghani R, Kooti W (2016) The Effect of Hemiscorpius lepturus (Scorpionida: Hemiscorpiidae) Venom on Leukocytes and the Leukocyte Sub-groups in Peripheral Blood of Rat. J Ar-thropod Borne Dis. 10(2): 159–167.
44. Shayesteh AA, Zamiri N, Peymani P, Zar-gani FJ, Lankarani KB (2011) A novel management method for disseminated in-travascular coagulation like syndrome af-ter a sting of Hemiscorpius lepturus: a case series. Trop Biomed. 28: 518–523.
45. Rahmani AH, Jalali A (2012) Symptom pat-terns in adult patients stung by scorpions with emphasis on coagulopathy and he-moglubinuria. J Venom Anim Toxins Incl Trop Dis. 18(4): 427–431.
46. Valavi E, Ansari MA (2008) Hemolytic uremic syndrome following Hemiscor-pius lepturus (scorpion) sting. Indian J. Nephrol. 18(4): 166–168.
47. Mirakabbadi A, Zolfagharian H, Hedayat A, Jalali A (2007) Clinical and biochemi-cal manifestation produced by scorpion (Hemiscorpius lepturus) venom in experi-mental animals. J Venom Anim Toxins Incl Trop Dis. 13(4): 758–765.
48. Seyedian R, Jalali A, Babaee MH, Pipelza-deh MH, Rezaee S (2012) A biodistri-bution study of Hemiscorpius lepturus scorpion venom and available polyclonal antivenom in rats. J Venom Anim Tox-ins Incl Trop Dis. 18(4): 375–383.
49. Jalali A, Pipelzadeh MH, Seyedian R, Rah-mani AH, Omidian N (2011) In vivo phar-macological study on the effectiveness of available polyclonal antivenom against Hemiscorpius lepturus venom. J Venom Anim Toxins Incl Trop Dis. 17(2): 142–149.
50. Kassiri H, Teimouri A, Shemshad M, Shar-ifinia N, Shemshad K (2012) Epidemio-logical survey and clinical presentation on scorpionism in south-west of Iran. Middle-East J Sci Res. 12(3): 325–330.
51. Zare Ma, Jalali A, Jahromi Ea, Vatanpur H, Akbary A (2006) Biochemical changes and manifestation of envenomation pro-duced by Odonthobuthus doriae venom in rabbits. J Venom Anim Toxins Incl Trop Dis. 12: 67–77.
52. Jalali A, Vatanpour H, Hosseininasab Z, Rowan EG, Harvey AL (2007) The ef-fect of the venom of the yellow Iranian scorpion Odontobuthus doriae on skele-tal muscle preparations in vitro. Toxi-con. 50(8): 1019–1026.
53. Radmanesh M (1990) Androctonus crassi-cauda sting and its clinical study in Iran. J Trop Med Hyg. 93: 323–326.
54. Shahi M, Rafinejad J, Az-Khosravi L, Moosavy SH (2015) First report of death due to Hemiscorpius acanthocercus en-venomation in Iran: Case report. Elec-tron Physician. 7(5): 1234–1238.
55. Oukkache N, Jaoudi RE, Ghalim N, Chgoury F, Bouhaouala B, Mdaghri NE, Sabatier JM (2014) Evaluation of the lethal po-tency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes. Toxins. 6 (6): 1873–1881.
56. Navidpour S, Lowe G (2009) Revised di-agnosis and redescription of Apistobuthus susanae (Scorpiones, Buthidae). J Arach-nol. 37(1): 45–59.
57. Mohammadi-Bavani M, Rafinejad J, Hanafi-Bojd AA, Oshaghi MA, Navidpour S, Dabiri F, Badakhshan M, Ghorbani G, Bagheri M (2017) Spatial distribution of medically important scorpions in north west of Iran. J Arthropod Borne Dis. 11 (3): 373–382.
58. Soleglad ME, Fet V, Kovařík F (2005) The systematic position of the scorpion gen-era Heteroscorpion Birula, 1903 and Uro-dacus Peters, 1861 (Scorpiones: Scorpi-onoidea). Euscorpius. 20: 1–38.
59. Prendini L (2000) Phylogeny and classifi-cation of the superfamily Scorpionoidea latreille 1802 (Chelicerata, Scorpiones): An exemplar approach. Cladistics. 16: 1–78.
60. Prendni L, Wheeler WC (2005) Scorpion higher phylogeny and classification, tax-onomic anarchy, and standards for peer review in online publishing. Cladistics. 21(5): 446–494.
61. Soleglad ME, Fet V (2003) High-level sys-tematics and phylogeny of the extent Scor-pions (Scorpions: Orthosterni). Euscorpius. 11: 1–175.
62. Prendini L (2011) Order Scorpiones C.L. Koch, 1850. In Animal Biodiversity: An Outline of Higher-Level Classification and Survey of Taxonomic Richness; Zhang ZQ, Ed., Zootaxa: Auckland, New Zea-land. 3148: 115–177.
63. Santibáñez-López CE, Francke OF, Ureta C, Possani LD (2016) Scorpions from Mex-ico: From species diversity to venom com-plexity. Toxins. 8(1): 2.
64. Rein-Ove J, Scorpion Files (2014) Tronheim. Norwegian University of Science and Technology. Available at: http://www.ntnu.no/ub/scorpion-files (accessed on 21 March 2017).
65. Soleglad ME, Fet V (2008) Contributions to scorpion systematics. III. Subfamilies Smeringurinae and Syntropinae (Scorpi-ones: Vaejovidae). Euscorpius. 71: 1–115.
66. Lowe G (2016) Two new Hemiscorpius Pe-ters, 1861 (Scorpiones: Hemiscorpiidae) from Northern Oman. Euscorpius. 2010 (91): 1–24.
67. Monod L, Lourenço WR (2005) Hemiscor-piidae (Scorpiones) from Iran, with de-scriptions of two new species and notes on biogeography and phylogenetic rela-tionships. Rev Suisse Zool. 112(4): 869–941.
68. Dehghani R, Kamiabi F, Mohammadi M (2018) Scorpionism by Hemiscorpius spp. in Iran: a review. J Venom Anim Toxins Incl Trop Dis. 24(1): 8.
69. Dehghani R, Khoobdel M, Sobati H (2018) Scorpion Control in Military Units: A Review Study. J Mil Med. 20(1): 3–13.
70. Dehghani R, Kamiabi F, Kassiri H, Hash-emi A, Mohammadzadeh N, Gharagazloo F (2018) A Study on Litter Size in Sev-eral Important Medical Scorpions Species (Arachnida: Scorpionida), Iran. J Entomol. 15: 155–160.
71. Dehghani R, Kassiri H (2018) A Checklist of Scorpions in Iran (By 2017). Asian J Pharm. 12(3): 880–887.
72. Mostafaii G, Dehghani R, Najafi M, Moosa-vi G, Rajaei M, Moghadam VK, Takhtfiroozeh S (2017) Frequency of urban pests and pesticides consumption in the residential houses of the east of Teh-ran City, Iran. J Entomol Res. 41: 125–132.
73. Dehghani R, Limoee M, Zarghi I (2012) The review of pesticide hazards with empha-sis on insecticide resistance in arthropods of health risk importance. Sci J Kurdi-stan Univ Med Sci. 17: 82–98 (Persian).
74. Kazemi-Moghaddam V, Dehghani R, Hadei M, Dehqan S, Sedaghat MM, Latifi M, Alavi-Moghaddam S (2018) Rodent-borne and rodent-related diseases in Iran. Comp Clin Pathol. pp. 1–13.
75. Dehghani R, Sedaghat MM, Bidgoli MS (2012) Wound myiasis due to Musca do-mestica (Diptera: Muscidae) in Persian horned viper, Pseudocerastes persicus (Squamata: Viperidae). J Arthropod Borne Dis. 6: 86–89.
How to Cite
Dehghani R, Charkhloo E, Seyyedi-Bidgoli N, Chimehi E, Ghavami-Ghameshlo M. A Review on Scorpionism in Iran. J Arthropod Borne Dis. 12(4):325-333.
Review Article