Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever

  • Fazilet Duygu Public Health Institution of Turkey, Ankara, Turkey
  • Tugba Sari Public Health Institution of Turkey, Ankara, Turkey
  • Turan Kaya Tokat State Hospital, Department of Infectious Diseases and Clinical Microbiology, Tokat, Turkey
  • Nermin Bulut Gaziosmanpasa University Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Tokat, Turkey
Keywords:
Crimean-Congo hemorrhagic fever, Haemorrhagic fever, Brucellosis, Zoonosis

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is a fatal zoonotic viral disease caused by infection with a tick-borne virus of the genus Nairovirus. In this study, we investigated the incidence of brucellosis in patients diag­nosed with CCHF.Methods: Overall, 169 patients hospitalized with an initial diagnosis of CCHF were included in 2011 in To­kat/ Turkey. Immunoglobulin M (IgM) antibodies and/or PCR results were used in the laboratory diagnosis of CCHF, while plate and standard tube agglutination (STA) tests were used to diagnose brucellosis.Results: Overall, 120 patients (79%) with positive PCR tests were diagnosed with CCHF. Five (4.16%) were also diag­nosed with brucellosis based on the positive plate and STA test results. Four patients (2.36%) had negative CCHF PCR and positive STA test results.Conclusion: Brucellosis and CCHF can mimic each other and that all patients with CCHF or brucellosis should be screened for both conditions.

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Published
2017-12-30
How to Cite
1.
Duygu F, Sari T, Kaya T, Bulut N. Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever. J Arthropod Borne Dis. 11(4):463-468.
Section
Original Article