Seroprevalence Study on West Nile Virus (WNV) Infection, a Hidden Viral Disease in Fars Province, Southern Iran

  • Masoumeh Amin Department of Medical Entomology and Vector Control, School of Health, Tehran University of Medical Sciences, Tehran, Iran AND Department of Medical Entomology and Vector Control, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  • Morteza Zaim Department of Medical Entomology and Vector Control, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • Hamideh Edalat Mail Department of Medical Entomology and Vector Control, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • Hamid Reza Basseri Department of Medical Entomology and Vector Control, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Reza Yaghoobi-Ershadi Department of Medical Entomology and Vector Control, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • Farhad Rezaei Department of Medical Virology, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • Kourosh Azizi Department of Medical Entomology and Vector Control, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mostafa Salehi-Vaziri Department of Arboviruses and Viral Hemorrhagic Fevers (National Ref Lab), Pasteur Institute of Iran, Tehran, Iran
  • Mohsen Ghane Department of Clinical Sciences, School of Veterinary Science, Shiraz University, Shiraz, Iran
  • Saideh Yousefi-Sharikabad Department of Medical Entomology and Vector Control, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • Sorna Dabaghmanesh Department of Medical Entomology and Vector Control, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  • Sedigheh Kheirandish Department of Oral and Maxillofacial Pathology, Bushehr University of Medical Sciences, Bushehr, Iran
  • Mohammad Esmaeil Najafi Environmental Health Unit, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  • Jalal Mohammadi Department of Medical Entomology and Vector Control, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
Keywords:
West nile virus; Seroprevalence; Iran

Abstract

Background: West Nile Virus, a mosquito-borne flavivirus, causes a variety of symptoms in human, from asymp­tomatic infection to neuroinvasive disease. Several studies have been conducted on the seroprevalence of WNV in­fection in dif­ferent areas from Iran. This study was performed to find the presence of antiviral antibodies in human serum among some high risk population and awareness of health care staff about symptom of the WNV infection.Methods: Study performed in five geographical districts based on high population of immigrant and do­mestic birds and prevalence of the antiviral antibodies in horses which was reported previously. Totally 150 human blood sam­ples were collected during 2018. The samples collected from patients referred to the clinics. The ELISA method used to detect IgG and IgM antibody against WNV. Logistic regression models used to analyze the effect of sex, age, keeping birds and urban/rural residence on the risk of infection. The awareness of health care staff about symp­tom of infection surveyed.Results: From all blood donors, 41 samples (27.33%) showed positive to IgG antibody. From which 56.10% were males and remaining females. None of the mentioned factors had a significant relationship. Health care staff had less attention to the infection. Conclusions: Although the prevalence of antibodies was relatively high, due to the similarity to other viral diseases, health care staff had less attention to the disease. The study showed that people in these areas have been exposed to the virus. Further research activities are recommended for control of this arbovirus.

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Published
2020-05-03
How to Cite
1.
Amin M, Zaim M, Edalat H, Basseri HR, Yaghoobi-Ershadi MR, Rezaei F, Azizi K, Salehi-Vaziri M, Ghane M, Yousefi-Sharikabad S, Dabaghmanesh S, Kheirandish S, Najafi ME, Mohammadi J. Seroprevalence Study on West Nile Virus (WNV) Infection, a Hidden Viral Disease in Fars Province, Southern Iran. J Arthropod Borne Dis. 14(2):173–184.
Section
Original Article